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Jamal Anderson ran for a career-high 188 yards and a touchdown and 44-year-old Steve DeBerg, who replaced Tony Graziani at halftime, threw a 29-yard touchdown pass to Terance Mathis as Atlanta (10-2) clinched a playoff berth.
The Falcons led 3-0 at the half, but Tony Horne of the Rams (2-10) returned the second-half kickoff 101 yards for a score.
