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No. 13 Kansas at No. 19 South Florida

7 p.m., Friday, ESPN2

Kansas normally gets its kicks from hosting Division IV teams before Big 12 play, so give the Jayhawks credit for branching out.

Iowa State at Iowa

11 a.m., Big Ten Network

Kirk Ferentz is just 3-6 against Iowa State, but can the Hawkeyes possibly lose to a Cyclones team Kent State outgained one week ago (albeit in a 48-28 victory)?

Michigan at Notre Dame

2:30 p.m., WMAQ-Ch. 5

Notre Dame will unveil a Lou Holtz statue before the game. After watching how the Irish played against San Diego State, fans might wonder: Could Holtz’s likeness out-coach Charlie Weis?

No. 16 Oregon at Purdue

2:30 p.m., WLS-Ch. 7

Purdue has lost 14 straight to ranked opponents. And Oregon’s offense, by the way, ranks No. 1 in the nation.

No. 5 Ohio State at No. 1 USC

7 p.m., WLS-Ch. 7

Chris “Beanie” Wells is now doubtful for the game after experiencing soreness in his injured right foot. Can OSU still win? That’s also doubtful.

No. 10 Wisconsin at No. 21 Fresno State

9:30 p.m., ESPN2

Badgers will get a massive boost from the return of tight end Travis Beckum (hamstring) and linebacker Jonathan Casillas (knee).