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CHICAGO, April 7 (Reuters) – Drugmaker Roche Holding AG

may be willing to up the ante in its attempt to buy

Illumina Inc., a disease fighter, after a

recommendation that Illumina’s shareholders reject its latest

hostile offer, Roche said in a statement on Friday.

“We remain willing to consider additional value if given the

opportunity to enter discussions and perform due diligence,”

said Severin Schwan, CEO of Roche Group.

Proxy advisory firm Institutional Shareholder Services (ISS)

said on Friday in its recommendation to reject the offer that

Roche’s $6.7 billion bid for San Diego-based Illumina

undervalues the firm.

Schwan said Roche was disappointed over the recommended

rejection of the bid for Illumina. But “we are pleased that ISS

noted that Roche would seem to be an excellent partner for

Illumina as the sequencing industry grows more intertwined with

new drug development,” he said.

Swiss-based Roche is the world’s largest maker of cancer

drugs and Illumina is a maker of machines that search the human

genome for ways to defeat disease.

Roche bid $44.50 per share early in the year and bumped the

offer to $51 at the end of March. Illumina, whose stock was

listed at $52.33 per share at Thursday’s close, rejected both

offers. Roche said the latest offer represented an approximate

$6.8 billion bid “on a fully diluted basis.”

Roche also has nominated a slate of candidates who will seek

election to Illumina’s board of directors at the April 18

meeting and proposed certain other matters, the statement said.