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* Icahn threatens proxy battle if board refuses sale

* Criticizes board for approving public offering of stock

* Amylin shares closed at $24.10 on Tuesday

April 4 (Reuters) – Activist investor Carl Icahn lashed out

at the board of Amylin Pharmaceuticals Inc on

Wednesday, urging it to put the company up for sale and

threatening a proxy fight.

Icahn, the company’s third-largest shareholder with an 8.9

percent stake, criticized Amylin for failing to confirm or deny

media reports that it had rejected a takeover offer from

Bristol-Myers Squibb Co of $22 a share, or $3.5 billion.

Bristol has also declined to comment on the reports.

In an open letter to Amylin, Icahn also criticized the board

for approving a public offering of 10 percent of the company at

an assumed price of $15.62 a share on March 8, without

disclosing any Bristol offer in the registration statement, and

for granting options to the company’s executive officers with an

exercise price of $16.02 a share on March 6.

“These actions make absolutely no sense to me in light of a

Bristol-Myers bid and have served to substantially dilute

shareholders who owned the stock when these actions were taken,”

Icahn wrote.

A spokeswoman for Amylin did not immediately respond to a

request for comment on Wednesday.

Icahn said a proxy contest right now would be a costly

distraction, “but I would not shy away from that possibility if

I felt that the Board was not pursuing seriously the opportunity

to sell the company.”

Amylin shares closed at $24.70 Tuesday on Nasdaq.