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* First nuclear talks in 15 months aimed at easing tension

* No major breakthrough expected in Saturday’s meeting

* But could pave ground for further negotiations

* West wants Iran to stop higher-grade enrichment

(Adds analyst quotes, detail, background)

By Fredrik Dahl and Justyna Pawlak

ISTANBUL, April 13 (Reuters) – Iran and the six world powers

prepared on Friday for rare talks aimed at easing fears that a

deepening dispute over the Islamic Republic’s nuclear programme

could plunge the Middle East into a new war.

Officials from Iran and the six major powers arrived in

Istanbul ahead of Saturday’s bid to restart stalled diplomacy

following months of soaring tension and persistent speculation

that Israel might attack Iranian nuclear sites.

The meeting is widely seen as a chance for the powers – the

United States, France, Russia, China, Britain and Germany – and

Iran to halt a downward diplomatic spiral and start to seek ways

out of years of deadlock.

The West accuses Iran of seeking to develop a nuclear

weapons capability and Israel has hinted at pre-emptive military

strikes to prevent its arch foe from obtaining such arms.

Iran, which has come under increasingly tough Western

sanctions targeting its oil exports, says its nuclear programme

is peaceful and has repeatedly ruled out suspending it.

Diplomats and analysts played down any expectations of a

major breakthrough in the first round of discussions, but said

the meeting may pave the ground for further negotiations aimed

at resolving the decade-long row.

Western officials have made clear their immediate priority

is to convince Tehran to cease the higher-grade uranium

enrichment it started in 2010. Iran has since sharply expanded

that work, shortening the time it would need for any weapons

“break out”.

Iran has signalled some flexibility over halting this work –

refining uranium to a fissile purity of 20 percent compared with

the 5 percent level required for power plants – but also

suggests it is not ready to do so yet.

The talks “will begin a very complex negotiation, and for

several months diplomacy will take some pressure off oil prices

and help keep the chance of Israeli strikes very low,” said

Cliff Kupchan, a Middle East analyst at the Eurasia Group.

But in the end, Kupchan said renewed diplomacy was unlikely

to yield a resolution to the crisis, which has helped push

global oil prices higher this year.

TRUST DEFICIT

Iranian state television showed footage of Iranian chief

nuclear negotiator Saeed Jalili getting into a car at the

airport of Turkey’s biggest city.

“The head of Iran’s Supreme National Security Council, Saeed

Jalili, arrived in Istanbul on Friday and was welcomed by local

officials as well as Iran’s envoy to Turkey, Bahman

Hosseinpour,” Iran’s official IRNA news agency said.

Jalili headed a four-member Iranian delegation, state

television said. An Iranian news agency later said his deputy

Ali Baqeri held talks with a senior Chinese official in Istanbul

on Friday and would also meet a Russian delegate.

The formal talks with the six powers and their chief

representative, European Union foreign policy chief Catherine

Ashton, will get underway on Saturday, but Ashton and Jalili are

expected to meet over dinner on Friday evening.

The last time the two sides met, also in Istanbul in January

last year, they could not even agree an agenda.

Both sides signalled in the run-up to Saturday’s discussions

their intent to give diplomacy a real chance.

“We hope that this first round will produce a conducive

environment for concrete results through a sustained process,”

Ashton’s spokesman Michael Mann said in an email.

Iranian Foreign Minister Ali Akbar Salehi, in a rare opinion

piece in a U.S. newspaper, said his country hoped that all sides

would commit to comprehensive dialogue and that negotiators make

“genuine efforts to reestablish confidence and trust”.

Defying toughening sanctions, Iran has continued to expand

its uranium enrichment programme – activity which can have both

civilian and military purposes – and experts say it now has

enough material for four atomic bombs if processed much further.

Mark Fitzpatrick, a director of the International Institute

for Strategic Studies think-tank, said getting Iran to halt 20

percent enrichment would be an interim goal “to put a lid on the

most troublesome” aspect of Iran’s nuclear programme.

A long-term deal will have to “provide confidence that Iran

cannot quickly produce nuclear weapons,” he told Reuters, adding

this would require both better monitoring of Iran’s nuclear work

and limits on its uranium enrichment and stockpiles.

(Additional reporting by Zahra Hosseinian, Jonathan Burch,

Alexandra Hudson, Ayla Jean Yackley and Ece Toksabay; Editing by

Jon Hemming)