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* Q1 EPS misses Street: $1.34 vs $1.40 analyst view

* Reserves for medical claim costs in focus

* Aetna backs 2012 profit outlook

* Shares fall 8 percent

(Adds CFO, analyst comments, updates stock price)

By Lewis Krauskopf

April 26 (Reuters) – Aetna Inc signaled that health

claim costs may be on the verge of rising as its quarterly

profit missed Wall Street’s target, sending shares of the No. 3

U.S. health insurer down more than 8 percent.

Health insurers largely posted higher-than-expected earnings

in 2011 because of Americans’ low use of medical services in the

weak economy, leading their shares to far outperform the broader

stock market.

But Aetna executives said on Thursday that they were seeing

a stabilization in medical claims costs after deceleration that

helped profits for the past year.

“Are we seeing a turn in healthcare cost utilization?” said

Tim Nelson, a senior healthcare analyst with Nuveen Asset

Management. “That’s what Aetna investors are worried about,

that’s what managed care investors are worried about.”

Shares of rival health insurers were down modestly after

Aetna’s report. WellPoint Inc and Cigna Corp fell

more than 1.2 percent, while UnitedHealth Group Inc

slipped nearly 1 percent.

Aetna, whose shares had outperformed rivals this year, is

the first major health insurer to miss earnings estimates for

the first quarter, after UnitedHealth and WellPoint posted

higher-than-expected profits.

While UnitedHealth and WellPoint also raised their

respective earnings forecasts for 2012, Aetna merely backed its

outlook.

“They missed and they reiterated guidance, and what the

Street was expecting was a beat and a guidance raise,” Nelson

said. Investors with wide-ranging sector portfolios “are going

to sell on that kind of result.”

In the past year, Aetna was able to recognize gains from the

money it sets aside to cover medical claims, when actual claims

submitted turned out to be lower than the company had forecast.

Analysts were expecting that trend to continue in the first

quarter of 2012, but Aetna said it did not benefit from any such

gains during the period.

“We do not see trend decelerating any further,” Aetna Chief

Executive Officer Mark Bertolini said of medical claims costs on

a conference call. “From a utilization standpoint, we don’t see

anything that is alarming in the marketplace.”

For 2012, the executives said the company was keeping its

current projection for medical claim costs, which calls for a

slight increase over the year before. They noted it was very

early in the year to draw many conclusions and that the company

had so far reserved appropriately.

“We did predict and forecast an increase in utilization into

2012,” Aetna Chief Financial Officer Joseph Zubretsky said in an

interview. “We saw nothing in the first quarter that would allow

us or steer us to change that forecast.”

Aetna shares were down 8.2 percent at $45.33 on Thursday

afternoon on the New York Stock Exchange. Through Wednesday,

Aetna shares had risen about 17 percent this year, compared with

a 14 percent rise for the Morgan Stanley Healthcare index

of health insurers.

MISS DISAPPOINTS

Aetna’s first-quarter net income fell to $511 million, or

$1.43 per share, from $586 million or $1.50 per share a year

earlier.

Excluding items, earnings of $1.34 a share missed the

analysts’ average estimate by 6 cents, according to Thomson

Reuters I/B/E/S.

Revenue rose 6 percent to $8.92 billion.

“The main issue that people are having with this quarter is

they missed consensus slightly and some of what they’re saying

about their reserves for medical costs is confusing,” said Sarah

James, an analyst with Wedbush Securities.

In the interview, Zubretsky said investors should take note

of Aetna’s revenue increase and strong profit margins.

“What I would tell people to be focused on is the quality of

the operating metrics underlying our first-quarter result,” he

said.

Aetna spent 81.5 percent of premium revenue on medical

claims, up from 79.2 percent a year earlier. Its operating

expenses rose nearly 7 percent.

Aetna’s membership stood at 17.92 million at the end of

March, up 0.6 percent from a year ago. The company expects

enrollment to swell to 18.2 million by year-end.

The insurer still expects operating earnings per share of

about $5.00 for 2012. Analysts are looking for $5.15.

(Reporting By Lewis Krauskopf in New York; Editing by Lisa Von

Ahn, Gerald E. McCormick and Matthew Lewis)