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May 13 (Reuters) – JPMorgan Chase & Co is expected

this week to accept the resignation of Chief Investment Officer

Ina Drew after the bank lost $2 billion or more with a failed

hedging strategy using derivatives, sources close to the matter

said on Sunday.

Two of Drew’s subordinates who were involved with the

trades, Achilles Macris and Javier Martin-Artajo, are expected

to be asked to leave, according to the people familiar with the

matter.